We’ve talked about benzene a bit already in this series, but did you know that benzene rings are present in all kinds of familiar substances? The styrofoam packaging that comes with new appliances, some pharmaceuticals, pesticides, and even some explosives contain benzene. In this episode of Crash Course Organic Chemistry, we’ll see how we can use electrophilic aromatic substitution to attach stuff to benzene rings like halogens, carbons, and more! Episode Sources: Rocke, A.J., 1985. Hypothesis and experiment in the early development of Kekule's benzene theory. Annals of Science, 42(4), pp.355-381. Martín, N. and Scott, L.T., 2015. Challenges in aromaticity: 150 years after Kekulé's benzene. Chemical Society Reviews, 44(18), pp.6397-6400. Stuttgart, G., 2018. Charles Friedel (1832–1899) And James Mason Crafts (1839–1917): The Friedel–Crafts Alkylation And Acylation Reactions. [online] Thieme.de. Available at: www.thieme.de/statics/bilder/thieme/final/en/bilder/tw_chemistry/CFZ-Synform-Charles-Friedel-James-Crafts-NRBio.pdf Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014. Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012. Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009. McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016. Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020. Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013. *** Watch our videos and review your learning with the Crash Course App! Download here for Apple Devices: apple.co/3d4eyZo Download here for Android Devices: bit.ly/2SrDulJ Crash Course is on Patreon! You can support us directly by signing up at www.patreon.com/crashcourse Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever: Shannon McCone, Amelia Ryczek, Ken Davidian, Brian Zachariah, Stephen Akuffo, Toni Miles, Oscar Pinto-Reyes, Erin Nicole, Steve Segreto, Michael M. Varughese, Kyle & Katherine Callahan, Laurel A Stevens, Vincent, Michael Wang, Stacey Gillespie, Jaime Willis, Krystle Young, Michael Dowling, Alexis B, Rene Duedam, Burt Humburg, Aziz, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Junrong Eric Zhu, Alan Bridgeman, Rachel Creager, Jennifer Smith, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, Brandon Westmoreland, team dorsey, Trevin Beattie, Divonne Holmes à Court, Eric Koslow, Jennifer Dineen, Indika Siriwardena, Khaled El Shalakany, Jason Rostoker, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, William McGraw, Andrei Krishkevich, ThatAmericanClare, Rizwan Kassim, Sam Ferguson, Alex Hackman, Jirat, Katie Dean, neil matatall, TheDaemonCatJr, Wai Jack Sin, Ian Dundore, Matthew, Justin, Jessica Wode, Mark, Caleb Weeks __ Want to find Crash Course elsewhere on the internet? Facebook - www.facebook.com/YouTubeCrashCourse Twitter - www.twitter.com/TheCrashCourse Tumblr - thecrashcourse.tumblr.com Support Crash Course on Patreon: patreon.com/crashcourse CC Kids: www.youtube.com/crashcoursekids

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