What Your Family History Can’t Tell You

submitted by Huzzaz on 11/12/19 1

Thanks to the National Human Genome Research Institute for supporting this episode. If you’re interested in learning more about the human genome and the latest in polygenic risk score research, head to genome.gov/PRS #polygenicriskscores #science The first time you visit a new doctor, they’ll probably ask you about your family history - but it turns out that family history doesn’t tell you everything about the risks that can be hidden in your genes. Hosted by: Hank Green SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at www.scishowtangents.org ---------- Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Eric Jensen, Matt Curls, Sam Buck, Christopher R Boucher, Avi Yashchin, Adam Brainard, Greg, Alex Hackman, Sam Lutfi, D.A. Noe, Piya Shedden, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters ---------- Looking for SciShow elsewhere on the internet? Facebook: www.facebook.com/scishow Twitter: www.twitter.com/scishow Tumblr: scishow.tumblr.com Instagram: instagram.com/thescishow ---------- Sources: www.ncbi.nlm.nih.gov/pmc/articles/PMC2987426/ academic.oup.com/hmg/article/23/22/6112/2900819 www.broadinstitute.org/news/depth-polygenic-risk-scoring www.nature.com/articles/s41588-018-0183-z jamanetwork.com/journals/jama/article-abstract/2730627 www.bmj.com/content/360/bmj.j5757 www.nature.com/articles/s41576-018-0018-x www.ncbi.nlm.nih.gov/pmc/articles/PMC6309089/ www.genome.gov/about-genomics/fact-sheets/Genome-Wide-Association-Studies-Fact-Sheet Image Sources: commons.wikimedia.org/wiki/File:PBB_Protein_BRCA2_image.jpg commons.wikimedia.org/wiki/File:Protein_BRCA1_PDB_1jm7.png commons.wikimedia.org/wiki/File:Manhattan_Plot.png commons.wikimedia.org/wiki/File:Dna-SNP.svg

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