From London Ontario -- Scientists have identified a new genetic mutation for amyotrophic lateral sclerosis (ALS), according to a report published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneratio. Researchers studied both familial and sporadic cases of the ALS, a debilitating neurological disease characterized by muscle atrophy, difficultly walking, swallowing and breathing and weakness. Researchers found mutations in the ARHGEF28 gene that were present in almost all cases of the disease. These results could potentially lead to new targeted therapies. We spoke with Dr. Michael Strong, principal investigator of this study, who offered some further insight