Visit www.asgct.org/education for more free resources on gene and cell therapy, including progress on a number of promising treatments already in development. Lots of genetic diseases come down to a small change in a single gene, but how do you treat those diseases when the cells involved don’t have any DNA? Hosted by: Hank Green SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at www.scishowtangents.org ---------- Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow ---------- Dooblydoo thanks go to the following Patreon supporters: Alex Schuerch, Alex Hackman, Andrew Finley Brenan, Sam Lutfi, D.A. Noe, الخليفي سلطان, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters ---------- Looking for SciShow elsewhere on the internet? Facebook: www.facebook.com/scishow Twitter: www.twitter.com/scishow Tumblr: scishow.tumblr.com Instagram: instagram.com/thescishow ---------- Sources: www.nature.com/articles/ng1092-93 www.fda.gov/newsevents/newsroom/pressannouncements/ucm589467.htm www.ncbi.nlm.nih.gov/pmc/articles/PMC1838946/ www.ncbi.nlm.nih.gov/pubmed/13852872/ ghr.nlm.nih.gov/condition/sickle-cell-disease#genes www.sciencedirect.com/science/article/pii/S0037196318300295 www.sciencedirect.com/science/article/abs/pii/S1465324918304869 www.nature.com/articles/549S28a www.nejm.org/doi/full/10.1056/nejmoa1609677 clinicaltrials.gov/ct2/show/NCT02151526 clinicaltrials.gov/ct2/show/NCT02186418 science.sciencemag.org/content/302/5644/400.summary www.nature.com/articles/s41375-018-0106-0 www.ncbi.nlm.nih.gov/pmc/articles/PMC110156/ www.nature.com/articles/nature20134 www.bloodjournal.org/content/early/2018/03/08/blood-2017-10-811505 www.the-scientist.com/news-opinion/us-companies-launch-crispr-clinical-trial-64746 Images: commons.wikimedia.org/wiki/File:1911_Sickle_Cells.jpg commons.wikimedia.org/wiki/File:Sickle_Cell_Anemia.png commons.wikimedia.org/wiki/File:Protein_HBB_PDB_1a00.png commons.wikimedia.org/wiki/File:Breast_cancer_cells.jpg commons.wikimedia.org/wiki/File:Difference_DNA_RNA-EN.svg www.istockphoto.com/vector/anemia-gm529560031-53891960 www.istockphoto.com/vector/3d-abstract-red-blood-cells-erythrocytes-illustration-gm528779549-53567530 www.istockphoto.com/vector/hematopoietic-stem-cell-gm499405345-42410804 www.istockphoto.com/photo/inside-body-gm178487169-2321069 www.istockphoto.com/vector/cute-emoticons-set-gm1027424576-275468879 www.istockphoto.com/photo/car-t-cell-therapy-gm871137890-145327349 www.istockphoto.com/photo/bone-tissue-structure-gm464902438-59347930 www.istockphoto.com/vector/human-internal-organ-color-icons-gm909009176-250382894 www.istockphoto.com/vector/structure-of-human-hemoglobin-gm508170217-45811410

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