Development of multiscale models for complex chemical systems: From H+H2 to biomolecules Martin Karplus, Université de Strasbourg, France and Harvard University, Cambridge, MA, USA Computer simulations of biological functions: From enzymes to molecular machines Arieh Warshel, University of Southern California, Los Angeles, CA, USA Birth & future of multi-scale modeling of biological macromolecules Michael Levitt, Stanford University School of Medicine, Stanford, CA, USA