In the second video of our two-part series on HIV and AIDS, we look at the challenges that have kept scientists from developing a cure, and the treatments that have still managed to improve the outlook for those infected. We're conducting a survey of our viewers! If you have time, please give us feedback: www.surveymonkey.com/r/SciShowSurvey2017 Hosted by: Hank Green ---------- Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow ---------- Dooblydoo thanks go to the following Patreon supporters: Kelly Landrum Jones, Sam Lutfi, Kevin Knupp, Nicholas Smith, Inerri, D.A. Noe, alexander wadsworth, سلطان الخليفي, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Bella Nash, Charles Southerland, Bader AlGhamdi, James Harshaw, Patrick Merrithew, Patrick D. Ashmore, Candy, Tim Curwick, charles george, Saul, Mark Terrio-Cameron, Viraansh Bhanushali, Kevin Bealer, Philippe von Bergen, Chris Peters, Justin Lentz ---------- Looking for SciShow elsewhere on the internet? Facebook: www.facebook.com/scishow Twitter: www.twitter.com/scishow Tumblr: scishow.tumblr.com Instagram: instagram.com/thescishow ---------- Sources: www.avert.org/about-hiv-aids/cure www.avert.org/professionals/hiv-science/searching-cure www.avert.org/professionals/hiv-science/overview aidsinfo.nih.gov/understanding-hiv-aids/infographics/25/fda-approval-of-hiv-medicines www.cdc.gov/mmwr/preview/mmwrhtml/00001409.htm www.cdc.gov/hiv/basics/whatishiv.html www.stat.wisc.edu/~larget/Genetics629/hiv.pdf www.cdc.gov/mmwr/preview/mmwrhtml/su6004a11.htm www.ihv.org/Education--Training/General-HIV-AIDS-Information/AIDS-Acquired-Immune-Deficiency-Syndrome--/ www.ncbi.nlm.nih.gov/pubmed/2863631 www.ncbi.nlm.nih.gov/pubmed/3548350 time.com/4705809/first-aids-drug-azt/ www.britannica.com/science/AZT americanhistory.si.edu/blog/2010/09/a-brief-history-of-azt.html www.ncbi.nlm.nih.gov/pmc/articles/PMC2815149/ www.nytimes.com/1987/03/21/us/us-approves-drug-to-prolong-lives-of-aids-patients.html?pagewanted=all www.nytimes.com/1989/08/28/opinion/azt-s-inhuman-cost.html www.niaid.nih.gov/diseases-conditions/hivaids www.merckmanuals.com/professional/infectious-diseases/human-immunodeficiency-virus-hiv/human-immunodeficiency-virus-hiv-infection www.ncbi.nlm.nih.gov/pmc/articles/PMC4058441/ www.ncbi.nlm.nih.gov/pmc/articles/PMC4396582/ www.medscape.org/viewarticle/523119 www.fda.gov/ForPatients/Illness/HIVAIDS/History/ucm151079.htm journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002251 www.cdc.gov/hiv/risk/art/index.html www.avert.org/professionals/hiv-programming/prevention/treatment-as-prevention www.cdc.gov/hiv/risk/prep/index.html www.aidsmap.com/Second-case-report-of-PrEP-failure-due-to-drug-resistant-virus/page/3093327/ www.nature.com/news/hopes-of-hiv-cure-in-boston-patients-dashed-1.14324 aidsinfo.nih.gov/understanding-hiv-aids/fact-sheets/19/93/what-is-a-latent-hiv-reservoir- www.fredhutch.org/en/news/center-news/2015/02/timothy-ray-brown-doctor-who-cured-him.html www.vox.com/science-and-health/2017/7/24/16019590/hiv-vaccine-international-aids-society-conference www.the-scientist.com/?articles.view/articleNo/50018/title/Resistance-to-HIV-Engineered-Via-CRISPR/ www.nejm.org/doi/full/10.1056/NEJMoa0802905#t=articleTop www.niaid.nih.gov/diseases-conditions/sustained-viral-remission-research journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002417 www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(17)30213-7 ww2.kqed.org/futureofyou/2017/09/28/research-dampens-hopes-of-hiv-cure-shows-progress-on-remission-without-drugs/ bmcmedicine.biomedcentral.com/articles/10.1186/s12916-015-0517-y Images: en.wikipedia.org/wiki/File:TEV_protease_summary.png