Could the club drug, ketamine, be the best hope for curing chronic depression? Every year millions of Americans struggle with major depression, but 30% of these people don’t get any better on anti-depressants. However, low dose ketamine infusions can offer complete relief from depressive thoughts and feelings in as little as 1-2 hours. Though the FDA hasn’t approved ketamine for psychiatric disorders, pioneering doctors have been administering ketamine in a practice known as “off-label” treatment in clinics popping up across the country. But with no FDA approval, no oversight, limited data and no regulations, some medical professionals are concerned patients are essentially lab mice, not realizing the potential risks with this “miracle drug." WATCH NEXT: The Cuban Punks Who Infected Themselves with HIV in Protest -- bit.ly/2kXEa2N Click here to subscribe to VICE: bit.ly/Subscribe-to-VICE Check out our full video catalog: bit.ly/VICE-Videos Videos, daily editorial and more: vice.com More videos from the VICE network: www.fb.com/vicevideo Like VICE on Facebook: fb.com/vice Follow VICE on Twitter: twitter.com/vice Read our Tumblr: vicemag.tumblr.com Follow us on Instagram: instagram.com/vice Check out our Pinterest: pinterest.com/vicemag Download VICE on iOS: apple.co/28Vgmqz Download VICE on Android: bit.ly/28S8Et0