Pre-order your NEAR Shoemaker pin all this month here: dftba.com/scishow Sometimes science surprises us with twists that we never could have predicted, and this is the case in the development of iPSCs. Hosted by: Rose Bear Don't Walk (she/her) SciShow is on TikTok! Check us out at www.tiktok.com/@scishow ---------- Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: scishow-tangents.simplecast.com/ Facebook: www.facebook.com/scishow Twitter: www.twitter.com/scishow Instagram: instagram.com/thescishow #SciShow #science #education ---------- Sources: pubmed.ncbi.nlm.nih.gov/16904174/ www.cell.com/cell/fulltext/S0092-8674(07)01471-7 link.springer.com/article/10.1007/s12015-021-10262-3 www.nature.com/scitable/definition/transcription-factor-167/ www.ncbi.nlm.nih.gov/pmc/articles/PMC3347549/ www.ncbi.nlm.nih.gov/pmc/articles/PMC3967385/ www.riken.jp/en/news_pubs/research_news/pr/2013/20130730_1/ www.nejm.org/doi/full/10.1056/NEJMoa1608368 pubmed.ncbi.nlm.nih.gov/29770269/ www.frontiersin.org/articles/10.3389/fcell.2015.00002/ful www.ncbi.nlm.nih.gov/pmc/articles/PMC8000082/ www.ncbi.nlm.nih.gov/pmc/articles/PMC8709242/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7441954/ www.nature.com/articles/s41467-017-00236-w journals.biologists.com/dev/article/144/11/1923/47944/Human-embryo-research-and-the-14-day-rule www.nature.com/articles/s41467-021-23294-7 pubmed.ncbi.nlm.nih.gov/20813264/ www.sciencedirect.com/science/article/pii/S0093691X16300954 www.sciencedirect.com/science/article/pii/S1359644618301405 Image Sources: commons.wikimedia.org/wiki/File:Human_induced_pluripotent_stem_cell_colony_(51816035910).jpg commons.wikimedia.org/wiki/File:Efficient-and-Reproducible-Myogenic-Differentiation-from-Human-iPS-Cells-Prospects-for-Modeling-pone.0061540.s011.ogv commons.wikimedia.org/wiki/File:Human_cheek_cell.jpg www.gettyimages.com/detail/illustration/illustration-of-neuron-anatomy-vector-royalty-free-illustration/1153647071?phrase=neuron&adppopup=true bit.ly/3hrzcKr commons.wikimedia.org/wiki/File:Final_stem_cell_differentiation_(1).svg commons.wikimedia.org/wiki/File:Shinya_yamanaka10.jpg www.frontiersin.org/articles/10.3389/fcell.2015.00002/full commons.wikimedia.org/wiki/File:Genetically-engineering-self-organization-of-human-pluripotent-stem-cells-into-a-liver-bud-like-ncomms10243-s2.ogv commons.wikimedia.org/wiki/File:Human_embryonic_stem_cells_only_A.png bit.ly/3NS6sqe www.gettyimages.com/detail/illustration/macular-degeneration-vector-medical-scheme-royalty-free-illustration/963177108?phrase=macular%20degeneration&adppopup=true commons.wikimedia.org/wiki/File:A-Novel-Serum-Free-Monolayer-Culture-for-Orderly-Hematopoietic-Differentiation-of-Human-Pluripotent-pone.0022261.s001.ogv commons.wikimedia.org/wiki/File:How_iPSC_Works_(46181969695).jpg www.gettyimages.com/detail/illustration/cell-engineering-and-cell-reprogramming-royalty-free-illustration/1429299555?phrase=ipsc&adppopup=true commons.wikimedia.org/wiki/File:Working_with_induced_pluripotent_stem_cells_(46291373691).jpg en.wikipedia.org/wiki/File:Humanstemcell.JPG www.gettyimages.com/detail/illustration/human-embryo-genesis-by-weeks-vector-cartoon-royalty-free-illustration/1290299851?phrase=embryo&adppopup=true www.gettyimages.com/detail/photo/home-caregiver-helping-a-senior-woman-standing-in-royalty-free-image/1397344064?phrase=parkinsons&adppopup=true www.frontiersin.org/articles/10.3389/fcell.2015.00002/full www.gettyimages.com/detail/photo/surgeon-with-organ-donation-royalty-free-image/160194832?phrase=organ%20transplant&adppopup=true www.gettyimages.com/detail/photo/wistar-rat-on-a-metal-table-royalty-free-image/530921257?phrase=lab%20rat&adppopup=true www.gettyimages.com/detail/photo/portrait-of-a-curious-little-piglet-looking-at-the-royalty-free-image/1367525280?phrase=pig&adppopup=true commons.wikimedia.org/wiki/File:Yamanaka.jpg commons.wikimedia.org/wiki/File:Induction_of_iPS_cells.svg solarsystem.nasa.gov/missions/near-shoemaker/in-depth/