Giuliana Rancic opened up to Kyle and Jackie O about the heartbreaking miscarriage her surrogate suffered. The news made headlines when Giuliana and husband Bill went public last week. Needless to say, building a family has been an uphill battle for the Rancics - in 2010, Giuliana herself suffered a miscarriage, in 2011 her breast cancer bout contributed to a tough time. A break from the heartache came with their son Duke; a result of a surrogate in August 2012... And you can hear how much Giuliana loves Duke when she chats with Kyle and Jackie O! Listen above.

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