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Warfarin/Coumadin Use, Part 1How warfarin/coumidin is used at the Palo Alto Medical Foundation -- testing, uses and risks of taking blood thinning medications. The information provided here is for your general information and education only, and should not be relied upon for personal diagnosis or treatment. Please consult with your personal physician before making any decisions.
Warfarin/Coumadin Use, Part 2How warfarin/coumidin is used at the Palo Alto Medical Foundation -- testing, uses and risks of taking blood thinning medications. The information provided here is for your general information and education only, and should not be relied upon for personal diagnosis or treatment. Please consult with your personal physician before making any decisions.
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WarfarinWARFARIN- anticoagulant
IND
- to prevent the formation of new blood clots and prevent existing blood clots from getting larger.
-Mode of action of warfarin: Interferes with the synthesis of vitamin K-dependent clotting factors.
HOW TO USE?
-The strength and colour of the tablet
1 mg - Apo-Warfarin (brown), Coumadin (pink)
2 mg - Apo-Warfarin (lavender), Coumadin (purple)
3 mg - Orfarin (blue).
5 mg - Apo-Warfarin (peach), Coumadin (peach), Orfarin (pink).
-Remind the patient not to remember the colour, remember the dose prescribed instead.
The dosage and administration
-Dose & duration based on indication and international normalised ratio (INR) target.
-Must be taken at the same time every day.
-If missed a dose for more than 8 hours, skip the dose and take the next dose (do not double the dose).
-To inform healthcare professionals (dentist, surgeon, doctor, pharmacist) if patient is planning to get pregnant, tooth extraction, or when getting consultation for medication, supplement or herbal remedies.
INR
-To check how long it takes for your blood to clot. The higher your INR is, the longer it takes for your blood to clot.
Target INR
-The targeted INR is 2-3 except for stroke prophylaxis in patients with mechanical heart valves such as mitral valves
(INR of 2.5-3.5).
-Follow the scheduled blood test and the counselling appointment made to achieve targeted INR as suggested by the doctor.
-Bring along anticoagulant booklet and all medications during the doctor/pharmacist appointment.
Side effects of medication
-Educate patient on symptoms of bleeding such as bruises of unknown cause, blood in urine/dark-coloured urine, black stools,gum bleeding or heavy menstrual bleeding.
-Report to doctor and pharmacist if any sign or symptom of bleeding occurs.
Drug-drug/food interactions
-Consult doctor and pharmacist before starting, stopping or changing dose of any medication/supplement, irregardless ofwhether it is a prescription or over-the-counter medication including traditional medicines.
-Monitor the intake of food which are rich in vitamin K such as green, leafy vegetables. Have consistent intake of vegetables and food with high content of high vitamin K.
-Follow a balanced and consistent diet.
-Review patient’s lifestyle such as alcohol consumption, smoking and stress. Advice to only consume small quantity of alcohol,
-stop smoking and manage stress as these will affect the therapy.
Pregnancy and breastfeeding
-Advise women with childbearing age that warfarin can have adverse effects on fetal development (first trimester), therefore,need to inform doctor if planning to get pregnant.
-Very little warfarin gets into the breast milk, therefore, it is safe to be taken if the mother is breastfeeding.
Thank You.
