Among diverse approaches to BsAbs production, knobs-in-holes BsAb technology has been extensively used. This technology refers to producing either a “knob” or a “hole” in each heavy chain to promote heterodimerization.
Among diverse approaches to BsAbs production, knobs-in-holes BsAb technology has been extensively used. This technology refers to producing either a “knob” or a “hole” in each heavy chain to promote heterodimerization.